A B C Z INF AP 

A02

Hepatitis C virus induced dysregulation of lipid metabolism and implications for HCC development

A03

Functional genetic dissection of hepatocarcinogenesis in NASH

A04

Platelet aggregation and activity in steatosis-HCC

A05

Function of the receptor for advanced glycation end products (RAGE) in inflammation-associated
liver carcinogenesis

A06

Role of atypical IκB protein IκBζ in HCC formation

B01

Linking chronic inflammation with tumor suppressor gene inactivation in liver cancer

B02

Metabolic reprogramming and control of autophagy in HCC progression

B03

Cooperative and exclusive functions of Hippo pathway effectors in hepato- carcinogenesis

B04

Nuclear Pore Complex (NPC) alterations and functional implications in hepatocarcinogenesis

B05

The role of epigenetic modifiers in liver cancer plasticity

B06

Defining the role of Notch signalling in the formation of cholangiocarcinoma

B07

Identification and functional characterization of cancer cell-derived, stroma-modulating factors in cholangiocarcinoma

C01

Optimization and evaluation of cmyc – directed liver cancer therapy

C02

Combinatorial targeting of epigenetic mechanisms in liver cancer

C03

HCC and the hepatic vascular niche: Analysis of angiocrine and adhesive vascular targets

C05

Microsphere-based immunotherapy of HCC

C06

Targeting the mutanome of liver cancer by viral oncolysis and tumor-directed immunotherapies

C07

Identification of molecular mechanisms conferring resistance to oncolytic viruses in HCC and implications for successful HCC virotherapy

Z01

Central administrative project

INF

Central Service Project: standardized biobanking, human probe and model system evaluation, data-base, bioinformatics

Associated Project Longerich

Plastizität von kombiniert hepatozellulär-cholangiozellulären Karzinomen

Associated Project Straub

Lipidtropfen und assoziierte Proteine bei chronischen Lebererkrankungen und in der Hepatokarzinogenese